1,4-Diazepan-5-one → 1-[3-(3-Chloro-4-fluorophenyl)prop-2-enoyl]-1,4-diazepan-5-one
Reaction equation
[Cl:1][c:2]1[cH:3][c:4]([CH:5]=[CH:6][C:7](=[O:8])[OH:9])[cH:10][cH:11][c:12]1[F:13].[NH:14]1[CH2:15][CH2:16][NH:17][C:18](=[O:21])[CH2:19][CH2:20]1>>[Cl:1][c:2]1[cH:3][c:4]([CH:5]=[CH:6][C:7](=[O:9])[N:14]2[CH2:15][CH2:16][NH:17][C:18](=[O:21])[CH2:19][CH2:20]2)[cH:10][cH:11][c:12]1[F:13]Participants
3
Sources & evidence
- ORD record
- ord-98e5b21e3b9140b59ad431a867438b31
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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