1-(2-Methoxyethyl)piperazine → 4-(1-(4-methoxybenzyl)-3-(4-(2-methoxyethyl)piperazin-1-yl)-1H-pyrazolo[3,4-b]pyridin-4-yloxy)-3-fluorobenzenamine

HRID 1124086Notes

Reaction equation

HRID 1124086 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][n:8]2[n:9][c:10]([I:26])[c:11]3[c:12]2[n:13][cH:14][cH:15][c:16]3[O:17][c:18]2[c:19]([F:25])[cH:20][c:21]([NH2:24])[cH:22][cH:23]2)[cH:27][cH:28]1.[CH3:29][O:30][CH2:31][CH2:32][N:33]1[CH2:34][CH2:35][NH:36][CH2:37][CH2:38]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][n:8]2[n:9][c:10]([N:36]3[CH2:35][CH2:34][N:33]([CH2:32][CH2:31][O:30][CH3:29])[CH2:38][CH2:37]3)[c:11]3[c:12]2[n:13][cH:14][cH:15][c:16]3[O:17][c:18]2[c:19]([F:25])[cH:20][c:21]([NH2:24])[cH:22][cH:23]2)[cH:27][cH:28]1

Participants

3

Reactant 2

HCID 27346381-(2-Methoxyethyl)piperazineHCID 672210033-Fluoro-4-((3-iodo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)oxy)aniline

Product 1

HCID 685138364-(1-(4-methoxybenzyl)-3-(4-(2-methoxyethyl)piperazin-1-yl)-1H-pyrazolo[3,4-b]pyridin-4-yloxy)-3-fluorobenzenamine

Sources & evidence

ORD record
ord-fe0aafb6efcf46e982ab58c3a4d5e469
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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