3-Chloro-4,7-difluorobenzo[b]thiophene-2-carbonyl chloride → tert-Butyl {4-[(3-chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl)-(4-methoxy-4'-sulfamoyl-biphenyl-3-ylmethyl)-amino]-cyclohexyl}-methyl-carbamate
Reaction equation
[CH3:1][O:2][c:3]1[c:4]([CH2:19][NH:20][CH:21]2[CH2:22][CH2:23][CH:24]([N:27]([C:28]([O:29][C:30]([CH3:31])([CH3:32])[CH3:33])=[O:34])[CH3:35])[CH2:25][CH2:26]2)[cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]([S:15]([NH2:16])(=[O:17])=[O:18])[cH:13][cH:14]2)[cH:7][cH:8]1.[Cl:36][c:37]1[c:38]2[c:39]([s:40][c:41]1[C:42](=[O:43])[Cl:44])[c:45]([F:50])[cH:46][cH:47][c:48]2[F:49]>>[CH3:1][O:2][c:3]1[c:4]([CH2:19][N:20]([CH:21]2[CH2:22][CH2:23][CH:24]([N:27]([C:28]([O:29][C:30]([CH3:31])([CH3:32])[CH3:33])=[O:34])[CH3:35])[CH2:25][CH2:26]2)[C:42]([c:41]2[c:37]([Cl:36])[c:38]3[c:39]([s:40]2)[c:45]([F:50])[cH:46][cH:47][c:48]3[F:49])=[O:43])[cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]([S:15]([NH2:16])(=[O:17])=[O:18])[cH:13][cH:14]2)[cH:7][cH:8]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-5f4090669c08403c905efef3a2b4a736
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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