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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1124263Generated: October 29, 2026

Dimethylformamide → 6-[2-(4-Chlorophenyl)ethenyl]-3-[4-[(3,3-difluoro-1-hydroxycyclobutyl)methoxy]-3-methoxyphenyl]pyrimidin-4-one

https://huagongshe.com/reaction/1124263

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantN,N'-DimethylethylenediamineHCID 8070—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant1-((4-Bromo-2-methoxyphenoxy)methyl)-3,3-difluorocyclobutanolHCID 67998448—
Reactant4-[2-(4-chlorophenyl)ethenyl]-1H-pyrimidin-6-oneHCID 136652483—
Product6-[2-(4-Chlorophenyl)ethenyl]-3-[4-[(3,3-difluoro-1-hydroxycyclobutyl)methoxy]-3-methoxyphenyl]pyrimidin-4-oneHCID 67997772—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-dff9fc1ca55e4c608b59e32d44dfed01
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)