Ethanol → tert-Butyl 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-piperidine-1-carboxylate

HRID 1124408Notes

Reaction equation

HRID 1124408 reaction equation
[CH3:27][CH2:28][OH:29].[H:25][H:26].[OH-:30].[OH-:32].[Pd+2:31].[c:1]1(-[n:7]2[n:8][n:9][c:10]([C:12]3=[CH:17][CH2:16][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:14][CH2:13]3)[cH:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[n:7]2[n:8][n:9][c:10]([CH:12]3[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]3)[cH:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 702EthanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 197052921-Tert-butoxycarbonyl-4-(1-phenyl-1,2,3-triazol-4-yl)-1,2,3,6-tetrahydropyridineHCID 178418361HCID 178418361, compound

Product 1

HCID 54072376tert-Butyl 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-piperidine-1-carboxylate

Sources & evidence

ORD record
ord-fb2f5383118443b49d92f67f70ab64a7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…