Dimethylamine → 7-(4-chlorophenyl)-2-((6-(dimethylamino)pyridin-3-yl)methyl)-8-(pyridin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one

HRID 1124492Notes

Reaction equation

HRID 1124492 reaction equation
[CH3:32][NH:33][CH3:34].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9](-[c:26]3[cH:27][cH:28][n:29][cH:30][cH:31]3)[c:10]3[n:11]([n:12][cH:13]2)[c:14](=[O:25])[n:15]([CH2:17][c:18]2[cH:19][n:20][c:21]([Cl:24])[cH:22][cH:23]2)[n:16]3)[cH:6][cH:7]1.[OH2:35]>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9](-[c:26]3[cH:27][cH:28][n:29][cH:30][cH:31]3)[c:10]3[n:11]([n:12][cH:13]2)[c:14](=[O:25])[n:15]([CH2:17][c:18]2[cH:19][n:20][c:21]([N:33]([CH3:32])[CH3:34])[cH:22][cH:23]2)[n:16]3)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 674DimethylamineHCID 962WaterHCID 119899567-(4-chlorophenyl)-2-((6-chloropyridin-3-yl)methyl)-8-(pyridin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one

Product 1

HCID 119888797-(4-chlorophenyl)-2-((6-(dimethylamino)pyridin-3-yl)methyl)-8-(pyridin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one

Sources & evidence

ORD record
ord-56eb75fb9b55455d85eca6af3cd611ad
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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