5-Chloro-2-[(5-chloropyridin-3-yl)oxy]nicotinic acid → tert-butyl 4-[1-[[5-chloro-2-[(5-chloro-3-pyridinyl)oxy]pyridine-3-carbonyl]amino]ethyl]benzoate

HRID 1124586Notes

Reaction equation

HRID 1124586 reaction equation
[Cl:1][c:2]1[cH:3][n:4][c:5]([O:11][c:12]2[cH:13][n:14][cH:15][c:16]([Cl:18])[cH:17]2)[c:6]([C:7](=[O:8])[OH:9])[cH:10]1.[NH2:19][CH:20]([CH3:21])[c:22]1[cH:23][cH:24][c:25]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[cH:33][cH:34]1>>[Cl:1][c:2]1[cH:3][n:4][c:5]([O:11][c:12]2[cH:13][n:14][cH:15][c:16]([Cl:18])[cH:17]2)[c:6]([C:7](=[O:9])[NH:19][CH:20]([CH3:21])[c:22]2[cH:23][cH:24][c:25]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[cH:33][cH:34]2)[cH:10]1

Participants

3

Reactant 2

HCID 575722875-Chloro-2-[(5-chloropyridin-3-yl)oxy]nicotinic acidHCID 59478590Tert-butyl 4-(1-aminoethyl)benzoate

Product 1

HCID 178464851tert-butyl 4-[1-[[5-chloro-2-[(5-chloro-3-pyridinyl)oxy]pyridine-3-carbonyl]amino]ethyl]benzoate

Sources & evidence

ORD record
ord-5d8c9aacbba549ef89e7cb8323fcbb0f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…