Dichloromethane → N-(2-Amino-5-methoxy-benzyl)-morpholine

HRID 1124612Notes

Reaction equation

HRID 1124612 reaction equation
[CH2:16]1[CH2:17][O:18][CH2:19][CH2:20][NH:21]1.[CH2:22]([Cl:23])[Cl:24].[NH2:1][c:2]1[c:3]([CH2:4][OH:5])[cH:6][c:7]([O:10][CH3:11])[cH:8][cH:9]1.[S:12]([Cl:13])([Cl:14])=[O:15]>>[NH2:1][c:2]1[c:3]([CH2:4][N:21]2[CH2:16][CH2:17][O:18][CH2:19][CH2:20]2)[cH:6][c:7]([O:10][CH3:11])[cH:8][cH:9]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8083MorpholineHCID 24386Thionyl ChlorideHCID 13756678(2-Amino-5-methoxyphenyl)methanol

Product 1

HCID 20318983N-(2-Amino-5-methoxy-benzyl)-morpholine

Sources & evidence

ORD record
ord-cdc19cb345d54479a5cc2a60f1386e81
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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