1-(Piperidin-4-yl)-4-(propan-2-yl)piperazine → 2-(3,4-dimethyl-benzyl)-1-[4-(4-isopropyl-piperazin-1-yl)-piperidin-1-yl]-4-[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin-1-yl]-butan-1,4-dione
Reaction equation
[CH3:1][c:2]1[cH:3][c:4]([CH2:5][CH:6]([C:7](=[O:8])[OH:9])[CH2:10][C:11]([N:12]2[CH2:13][CH2:14][CH:15]([N:18]3[C:19](=[O:28])[NH:20][c:21]4[cH:22][cH:23][cH:24][cH:25][c:26]4[CH2:27]3)[CH2:16][CH2:17]2)=[O:29])[cH:30][cH:31][c:32]1[CH3:33].[CH:34]([CH3:35])([CH3:36])[N:37]1[CH2:38][CH2:39][N:40]([CH:43]2[CH2:44][CH2:45][NH:46][CH2:47][CH2:48]2)[CH2:41][CH2:42]1>>[CH3:1][c:2]1[cH:3][c:4]([CH2:5][CH:6]([C:7](=[O:8])[N:46]2[CH2:45][CH2:44][CH:43]([N:40]3[CH2:39][CH2:38][N:37]([CH:34]([CH3:35])[CH3:36])[CH2:42][CH2:41]3)[CH2:48][CH2:47]2)[CH2:10][C:11]([N:12]2[CH2:13][CH2:14][CH:15]([N:18]3[C:19](=[O:28])[NH:20][c:21]4[cH:22][cH:23][cH:24][cH:25][c:26]4[CH2:27]3)[CH2:16][CH2:17]2)=[O:29])[cH:30][cH:31][c:32]1[CH3:33]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-75a2c61a542c4bc48ff982f1d350811c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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