1-(5-Aminopyridin-2-yl)azetidin-3-ol → N-[6-(3-Hydroxyazetidin-1-yl)pyridin-3-yl]-1-(3-fluorobenzyl)-5-trifluoromethyl-1H-indole-2-carboxamide
Reaction equation
[F:1][C:2]([c:3]1[cH:4][c:5]2[cH:6][c:7]([C:20](=[O:21])[OH:22])[n:8]([CH2:12][c:13]3[cH:14][c:15]([F:19])[cH:16][cH:17][cH:18]3)[c:9]2[cH:10][cH:11]1)([F:23])[F:24].[OH:25][CH:26]1[CH2:27][N:28]([c:30]2[n:31][cH:32][c:33]([NH2:36])[cH:34][cH:35]2)[CH2:29]1>>[F:1][C:2]([c:3]1[cH:4][c:5]2[cH:6][c:7]([C:20](=[O:22])[NH:36][c:33]3[cH:32][n:31][c:30]([N:28]4[CH2:27][CH:26]([OH:25])[CH2:29]4)[cH:35][cH:34]3)[n:8]([CH2:12][c:13]3[cH:14][c:15]([F:19])[cH:16][cH:17][cH:18]3)[c:9]2[cH:10][cH:11]1)([F:23])[F:24]Participants
3
Sources & evidence
- ORD record
- ord-010472e34944462d94749155294cddb8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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