Potassium Cation → 5-HT6/7 antagonist 1

HRID 1125052Notes

Reaction equation

HRID 1125052 reaction equation
[Br:17][CH2:18][CH2:19][N:20]1[C:21](=[O:30])[c:22]2[c:23]([cH:26][cH:27][cH:28][cH:29]2)[C:24]1=[O:25].[C:31](=[O:32])([O-:33])[O-:34].[CH3:38][C:39]#[N:40].[F:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([CH:9]3[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]3)[n:7][o:8]2)[cH:15][cH:16]1.[K+:35].[K+:36].[OH2:37]>>[F:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([CH:9]3[CH2:10][CH2:11][N:12]([CH2:18][CH2:19][N:20]4[C:21](=[O:30])[c:22]5[c:23]([cH:26][cH:27][cH:28][cH:29]5)[C:24]4=[O:25])[CH2:13][CH2:14]3)[n:7][o:8]2)[cH:15][cH:16]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6342AcetonitrileHCID 113251H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)-HCID 19660Carbonate IonHCID 8494213-(4-Piperidyl)-6-fluoro-1,2-benzisoxazole

Product 1

HCID 98653575-HT6/7 antagonist 1

Sources & evidence

ORD record
ord-e59748e5b74a45848be196741ce35955
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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