Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 112506Generated: October 30, 2026

Chloroform → 6-Acetyl-2-chloro-3-hydroxy-4-(2-trimethylsilylethynyl)pyridine

https://huagongshe.com/reaction/112506

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroformHCID 6212—
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantEthyl AcetateHCID 8857—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantIodide IonHCID 30165—
ReactantTrimethylsilylacetyleneHCID 66111—
Reactant6-Acetyl-2-chloro-3-hydroxy-4-iodo-pyridineHCID 18799558—
Product6-Acetyl-2-chloro-3-hydroxy-4-(2-trimethylsilylethynyl)pyridineHCID 18799586—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-3602c90c02354d74aefeb11dcb3f9866
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)