Bicarbonate Ion → 2-Benzyl-4-bromo-7-fluoro-2,3-dihydro-1H-isoindole
Reaction equation
[Br:1][c:2]1[c:3]([CH2:11][Br:12])[c:4]([CH2:9][Br:10])[c:5]([F:8])[cH:6][cH:7]1.[C:13](=[O:14])([O-:15])[OH:16].[CH3:26][C:27]#[N:28].[K+:17].[NH2:18][CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1>>[Br:1][c:2]1[c:3]2[c:4]([c:5]([F:8])[cH:6][cH:7]1)[CH2:9][N:18]([CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)[CH2:11]2Participants
6
Sources & evidence
- ORD record
- ord-5ba34fd9db4e4c10b5128eb6a3be7787
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…