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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1125320Generated: October 31, 2026

Acetic Acid → 3-[3-[3-(tert-Butyldimethylsilanyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)-4-oxoazetidin-2-yl]benzonitrile

https://huagongshe.com/reaction/1125320

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
Reactanttert-Butyl methyl etherHCID 15413—
ReactantTetrabutylammoniumHCID 16028—
ReactantFluoride IonHCID 28179—
ReactantBistrimethylsilylacetamidHCID 11708267—
Reactant3-[5-(tert-Butyldimethylsilanyloxy)-5-(4-fluorophenyl)-1-(4-fluorophenylamino)-2-(2-oxo-4-phenyloxazolidine-3-carbonyl)pentyl]benzonitrileHCID 22252068—
Product3-[3-[3-(tert-Butyldimethylsilanyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)-4-oxoazetidin-2-yl]benzonitrileHCID 22252076—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-1861b33f5c0540b3ad736eff8b0c5fb9
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)