tert-Butyl piperazine-1-carboxylate → 4-[5-(4-Iodo-3-methyl-phenylcarbamoyl)-pyridin-2-yl]-piperazine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:19](=[O:20])([O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[N:26]1[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]1.[C:32]([O:33][C:34]([N:35]1[CH2:36][CH2:37][N:38]([c:39]2[cH:40][cH:41][c:42]([C:43](=[O:44])[NH:45][c:46]3[cH:47][cH:48][c:49]([CH3:50])[c:51]([I:52])[cH:53]3)[cH:54][n:55]2)[CH2:56][CH2:57]1)=[O:58])([CH3:59])([CH3:60])[CH3:61].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[NH:8][c:9]2[cH:10][c:11]([CH3:16])[c:12]([I:15])[cH:13][cH:14]2)[cH:17][cH:18]1>>[c:2]1([N:29]2[CH2:28][CH2:27][N:26]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:31][CH2:30]2)[n:3][cH:4][c:5]([C:6](=[O:7])[NH:8][c:9]2[cH:10][c:11]([CH3:16])[c:12]([I:15])[cH:13][cH:14]2)[cH:17][cH:18]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-d24cecfc3e854612a95f278c32458727
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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