2,3-Dihydro-1-benzofuran-5-ylmethanamine → N2-[2,3-dihydrobenzo[b]furan-5-ylmethyl]-N4-(3,4-ethylenedioxyphenyl)-5-fluoro-2,4-pyrimidinediamine

HRID 1125360Notes

Reaction equation

HRID 1125360 reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([F:19])[c:6]([NH:8][c:9]2[cH:10][c:11]3[c:12]([cH:13][cH:14]2)[O:15][CH2:16][CH2:17][O:18]3)[n:7]1.[O:20]1[c:21]2[c:22]([cH:25][c:26]([CH2:29][NH2:30])[cH:27][cH:28]2)[CH2:23][CH2:24]1>>[c:2]1([NH:30][CH2:29][c:26]2[cH:25][c:22]3[c:21]([cH:28][cH:27]2)[O:20][CH2:24][CH2:23]3)[n:3][cH:4][c:5]([F:19])[c:6]([NH:8][c:9]2[cH:10][c:11]3[c:12]([cH:13][cH:14]2)[O:15][CH2:16][CH2:17][O:18]3)[n:7]1

Participants

3

Reactant 2

HCID 27353672,3-Dihydro-1-benzofuran-5-ylmethanamineHCID 220603622-chloro-5-fluoro-N-(3,4-ethylenedioxyphenyl)-4-pyrimidineamine

Product 1

HCID 22061054N2-[2,3-dihydrobenzo[b]furan-5-ylmethyl]-N4-(3,4-ethylenedioxyphenyl)-5-fluoro-2,4-pyrimidinediamine

Sources & evidence

ORD record
ord-b2609454d27a4a8388c5fc4b4ba95c2e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…