tert-Butyl 4-(4-chlorophenyl)-4-cyanopiperidine-1-carboxylate → 2-[4-(4-Chloro-phenyl)-piperidin-4-yl]-propan-2-ol

HRID 1125401Notes

Reaction equation

HRID 1125401 reaction equation
[C:1]([O:2][C:3]([N:4]1[CH2:5][CH2:6][C:7]([c:8]2[cH:9][cH:10][c:11]([Cl:12])[cH:13][cH:14]2)([C:15]#[N:16])[CH2:17][CH2:18]1)=[O:19])([CH3:20])([CH3:21])[CH3:22].[C:23]([O:24][C:25](=[O:26])[N:30]1[CH2:31][CH2:32][C:33]([C:36]([CH3:37])([CH3:38])[OH:39])([c:40]2[cH:41][cH:42][c:43]([Cl:46])[cH:44][cH:45]2)[CH2:34][CH2:35]1)([CH3:27])([CH3:28])[CH3:29]>>[NH:30]1[CH2:31][CH2:32][C:33]([C:36]([CH3:37])([CH3:38])[OH:39])([c:40]2[cH:41][cH:42][c:43]([Cl:46])[cH:44][cH:45]2)[CH2:34][CH2:35]1

Participants

3

Reactant 2

HCID 49760270tert-Butyl 4-(4-chlorophenyl)-4-cyanopiperidine-1-carboxylateHCID 667585124-(4-Chloro-phenyl)-4-(1-hydroxy-1-methyl-ethyl)-piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 231368852-[4-(4-Chloro-phenyl)-piperidin-4-yl]-propan-2-ol

Sources & evidence

ORD record
ord-819789f16c1b4a0d8c45c1ade17e104d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…