Dimethyl Sulfoxide → 5-{9-(Cyclopropylmethyl)-6-morpholin-4-yl-8-[3-(phenylsulfonyl)pyrrolidin-1-yl]-9H-purin-2-yl}pyrimidin-2-amine
Reaction equation
[CH3:42][S:43](=[O:44])[CH3:45].[Cl:15][c:16]1[n:17]([CH2:38][CH:39]2[CH2:40][CH2:41]2)[c:18]2[n:19][c:20](-[c:31]3[cH:32][n:33][c:34]([NH2:37])[n:35][cH:36]3)[n:21][c:22]([N:25]3[CH2:26][CH2:27][O:28][CH2:29][CH2:30]3)[c:23]2[n:24]1.[c:1]1([S:7](=[O:8])(=[O:9])[CH:10]2[CH2:11][NH:12][CH2:13][CH2:14]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([S:7](=[O:8])(=[O:9])[CH:10]2[CH2:11][N:12]([c:16]3[n:17]([CH2:38][CH:39]4[CH2:40][CH2:41]4)[c:18]4[n:19][c:20](-[c:31]5[cH:32][n:33][c:34]([NH2:37])[n:35][cH:36]5)[n:21][c:22]([N:25]5[CH2:26][CH2:27][O:28][CH2:29][CH2:30]5)[c:23]4[n:24]3)[CH2:13][CH2:14]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-3feb5f1a7a414b5c9df0c05e27313e24
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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