1-(2-(Benzyloxy)-5-fluorophenyl)cyclopropanamine → Methyl 3-[3-({1-[2-(benzyloxy)-5-fluorophenyl]cyclopropyl}amino)-5-bromo-2-oxopyrazin-1(2H)-yl]-5-fluoro-4-methylbenzoate

HRID 112577Notes

Reaction equation

HRID 112577 reaction equation
[Br:20][c:21]1[c:22](=[O:40])[n:23](-[c:28]2[cH:29][c:30]([C:31](=[O:32])[O:33][CH3:34])[cH:35][c:36]([F:39])[c:37]2[CH3:38])[cH:24][c:25]([Br:27])[n:26]1.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([C:16]2([NH2:19])[CH2:17][CH2:18]2)[cH:11][c:12]([F:15])[cH:13][cH:14]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([C:16]2([NH:19][c:21]3[c:22](=[O:40])[n:23](-[c:28]4[cH:29][c:30]([C:31](=[O:32])[O:33][CH3:34])[cH:35][c:36]([F:39])[c:37]4[CH3:38])[cH:24][c:25]([Br:27])[n:26]3)[CH2:17][CH2:18]2)[cH:11][c:12]([F:15])[cH:13][cH:14]1

Participants

3

Reactant 2

HCID 666889311-(2-(Benzyloxy)-5-fluorophenyl)cyclopropanamineHCID 66689945methyl 3-(3,5-dibromo-2-oxo-1(2H)-pyrazinyl)-5-fluoro-4-methylbenzoate

Product 1

HCID 66689772Methyl 3-[3-({1-[2-(benzyloxy)-5-fluorophenyl]cyclopropyl}amino)-5-bromo-2-oxopyrazin-1(2H)-yl]-5-fluoro-4-methylbenzoate

Sources & evidence

ORD record
ord-dd79825a5e1a446198ed159d38ebbed7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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