3-bromo-N-(2-(dimethylamino)ethyl)benzenesulfonamide → 3-[7-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-N-(2-dimethylamino-ethyl)-benzenesulfonamide
Reaction equation
[Br:25][c:26]1[cH:27][c:28]([S:32](=[O:33])(=[O:34])[NH:35][CH2:36][CH2:37][N:38]([CH3:39])[CH3:40])[cH:29][cH:30][cH:31]1.[F:1][CH:2]([c:3]1[cH:4][c:5](-[c:14]2[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12]#[CH:13])[F:24]>>[F:1][CH:2]([c:3]1[cH:4][c:5](-[c:14]2[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12]#[C:13][c:26]1[cH:27][c:28]([S:32](=[O:33])(=[O:34])[NH:35][CH2:36][CH2:37][N:38]([CH3:39])[CH3:40])[cH:29][cH:30][cH:31]1)[F:24]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-81672c39db28484ba883408aa4425326
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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