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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1125916Generated: October 31, 2026

1,2-Dichloroethane → methyl 4-[1-[4-[N'-(2-chlorophenyl)ureido]-3-methoxy phenylacetyl]-4,4-difluoro-2-pyrrolidinylmethoxy]benzoate

https://huagongshe.com/reaction/1125916

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantHydrochloric AcidHCID 313—
ReactantDimethylformamideHCID 6228—
ReactantEthyl AcetateHCID 8857—
Reactant4-(Dimethylamino)pyridineHCID 14284—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant4-[N'-(2-chlorophenyl)ureido]-3-methoxyphenylacetic acidHCID 23511867—
ReactantMethyl 4-(4,4-difluoro-2-pyrrolidinylmethoxy)benzoateHCID 23512388—
Productmethyl 4-[1-[4-[N'-(2-chlorophenyl)ureido]-3-methoxy phenylacetyl]-4,4-difluoro-2-pyrrolidinylmethoxy]benzoateHCID 69333413—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-402cc6a24620413da6e55d43558aebaa
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)