2-Chloromethyl-1-(2-trimethylsilanyl-ethoxymethoxy)-naphthalene → tert-butyl (3RS,4RS)-3-[1-(2-trimethylsilanyl-ethoxymethoxy)-naphthalen-2-ylmethoxy]-4-(4-trityloxymethyl-phenyl)-piperidine-1-carboxylate
Reaction equation
[Cl:42][CH2:43][c:44]1[c:45]([O:54][CH2:55][O:56][CH2:57][CH2:58][Si:59]([CH3:60])([CH3:61])[CH3:62])[c:46]2[cH:47][cH:48][cH:49][cH:50][c:51]2[cH:52][cH:53]1.[OH:1][CH:2]1[CH2:3][N:4]([C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([CH2:14][O:15][C:16]([c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)([c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[cH:12][cH:13]1>>[O:1]([CH:2]1[CH2:3][N:4]([C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([CH2:14][O:15][C:16]([c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)([c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[cH:12][cH:13]1)[CH2:43][c:44]1[c:45]([O:54][CH2:55][O:56][CH2:57][CH2:58][Si:59]([CH3:60])([CH3:61])[CH3:62])[c:46]2[cH:47][cH:48][cH:49][cH:50][c:51]2[cH:52][cH:53]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-e6d774346ef542d29a471faab1b20579
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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