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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1125959Generated: October 31, 2026

Chloride → Thiophene-3-carboxylic acid (6-{4-[3-(2-fluoro-5-trifluoromethylphenyl)ureido]phenyl}-1H-pyrazolo[3,4-b]pyridin-3-yl)amide

https://huagongshe.com/reaction/1125959

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantWaterHCID 962—
ReactantPyridineHCID 1049—
ReactantThiophene-3-carboxylic acidHCID 6918—
Reactant1-[4-(3-Amino-1H-pyrazolo[3,4-b]pyridin-6-yl)phenyl]-3-(2-fluoro-5-trifluoromethylphenyl)ureaHCID 178509220—
ProductThiophene-3-carboxylic acid (6-{4-[3-(2-fluoro-5-trifluoromethylphenyl)ureido]phenyl}-1H-pyrazolo[3,4-b]pyridin-3-yl)amideHCID 16095404—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-26099a1497994da39689346ed55566d7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)