2-(Piperazin-1-yl)-4-(trifluoromethyl)pyrimidine → (4-Methanesulfonyl-biphenyl-2-yl)-[4-(4-trifluoromethyl-pyrimidin-2-yl)-piperazin-1-yl]-methanone
Reaction equation
[CH3:17][S:18](=[O:19])(=[O:20])[c:21]1[cH:22][c:23]([C:33](=[O:34])[OH:35])[c:24](-[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[cH:25][cH:26]1.[N:1]1([c:7]2[n:8][cH:9][cH:10][c:11]([C:13]([F:14])([F:15])[F:16])[n:12]2)[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1>>[N:1]1([c:7]2[n:8][cH:9][cH:10][c:11]([C:13]([F:14])([F:15])[F:16])[n:12]2)[CH2:2][CH2:3][N:4]([C:33]([c:23]2[cH:22][c:21]([S:18]([CH3:17])(=[O:19])=[O:20])[cH:26][cH:25][c:24]2-[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)=[O:34])[CH2:5][CH2:6]1Participants
3
Sources & evidence
- ORD record
- ord-fcbc9e3a51144baaa90d71c11c049fd1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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