1-Fluoro-2-iodobenzene → (4-Amino-2-ethylsulfanyl-pyrimidin-5-yl)-(2-fluoro-phenyl)-methanone

HRID 1126080Notes

Reaction equation

HRID 1126080 reaction equation
[CH3:1][O:2][N:3]([C:4](=[O:5])[c:6]1[c:7]([NH2:15])[n:8][c:9]([S:12][CH2:13][CH3:14])[n:10][cH:11]1)[CH3:16].[F:17][c:18]1[c:19]([Li:24])[cH:20][cH:21][cH:22][cH:23]1.[F:25][c:26]1[cH:27][cH:28][cH:29][cH:30][c:31]1[I:32]>>[C:4](=[O:5])([c:6]1[c:7]([NH2:15])[n:8][c:9]([S:12][CH2:13][CH3:14])[n:10][cH:11]1)[c:19]1[c:18]([F:17])[cH:23][cH:22][cH:21][cH:20]1

Participants

4

Reactant 3

HCID 676731-Fluoro-2-iodobenzeneHCID 119748325-Pyrimidinecarboxamide, 4-amino-2-(ethylthio)-N-methoxy-N-methyl-HCID 178506686HCID 178506686, compound

Product 1

HCID 11975323(4-Amino-2-ethylsulfanyl-pyrimidin-5-yl)-(2-fluoro-phenyl)-methanone

Sources & evidence

ORD record
ord-333cec1dc60a4c41b009fdf014764fb1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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