Pyridine → Agomelatine

HRID 112654Notes

Reaction equation

HRID 112654 reaction equation
[CH3:16][C:17]([Cl:18])=[O:19].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[cH:7][cH:8][cH:9][c:10]([CH2:13][CH2:14][NH2:15])[c:11]2[cH:12]1.[cH:20]1[cH:21][cH:22][n:23][cH:24][cH:25]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[cH:7][cH:8][cH:9][c:10]([CH2:13][CH2:14][NH:15][C:17]([CH3:16])=[O:19])[c:11]2[cH:12]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 6367Acetyl chlorideHCID 110526677-Methoxy-1-naphthaleneethanamine

Product 1

HCID 82148Agomelatine

Sources & evidence

ORD record
ord-4e4676751bce4e05b9807747ff5e06b5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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