Thionyl Chloride → 5-Chloromethyl-4-methoxymethyl-6-methyl-2-(4-trifluoromethyl-phenyl)-pyrimidine
Reaction equation
[CH3:1][O:2][CH2:3][c:4]1[n:5][c:6](-[c:13]2[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[n:7][c:8]([CH3:12])[c:9]1[CH2:10][OH:11].[S:23]([Cl:24])([Cl:25])=[O:26]>>[CH3:1][O:2][CH2:3][c:4]1[n:5][c:6](-[c:13]2[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[n:7][c:8]([CH3:12])[c:9]1[CH2:10][Cl:25]Participants
3
Sources & evidence
- ORD record
- ord-81b84a69ade14eb78f4f07b57646a95f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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