2-Chloro-4-methylpyrimidine → 2-Propen-1-yl {3-[(2-chloro-4-pyrimidinyl)acetyl]-4-fluorophenyl}carbamate

HRID 1126970Notes

Reaction equation

HRID 1126970 reaction equation
[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([CH2:8][C:9](=[O:10])[c:11]2[cH:12][c:13]([NH:17][C:18]([O:19][CH2:20][CH:21]=[CH2:22])=[O:23])[cH:14][cH:15][cH:16]2)[n:7]1.[Cl:42][c:43]1[n:44][c:45]([CH3:46])[cH:47][cH:48][n:49]1.[F:24][c:25]1[cH:26][cH:27][c:28]([NH:29][C:30]([O:31][CH2:32][CH:33]=[CH2:34])=[O:35])[cH:36][c:37]1[C:38]([O:39][CH3:40])=[O:41]>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([CH2:8][C:9](=[O:10])[c:11]2[cH:12][c:13]([NH:17][C:18]([O:19][CH2:20][CH:21]=[CH2:22])=[O:23])[cH:14][cH:15][c:16]2[F:24])[n:7]1

Participants

4

Reactant 3

HCID 116296072-Chloro-4-methylpyrimidineHCID 579899812-Propen-1-yl {3-[(2-chloro-4-pyrimidinyl)acetyl]phenyl}carbamateHCID 57990057Methyl 2-fluoro-5-{[(2-propen-1-yloxy)carbonyl]amino}benzoate

Product 1

HCID 579897622-Propen-1-yl {3-[(2-chloro-4-pyrimidinyl)acetyl]-4-fluorophenyl}carbamate

Sources & evidence

ORD record
ord-d34b5e118b9641bd9394fa64b0bb36f4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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