4-chloro-N-[4-[[4-(piperidin-1-ylmethyl)-2-pyridinyl]oxy]but-2-enyl]butanamide → 4-(4,6-diaminopyrimidin-2-yl)sulfanyl-N-[4-[[4-(piperidin-1-ylmethyl)-2-pyridinyl]oxy]but-2-enyl]butanamide
Reaction equation
[N:1]1([CH2:7][c:8]2[cH:9][c:10]([O:14][CH2:15][CH:16]=[CH:17][CH2:18][NH:19][C:20]([CH2:21][CH2:22][CH2:23][Cl:24])=[O:25])[n:11][cH:12][cH:13]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[NH2:26][c:27]1[n:28][c:29]([SH:34])[n:30][c:31]([NH2:33])[cH:32]1>>[N:1]1([CH2:7][c:8]2[cH:9][c:10]([O:14][CH2:15][CH:16]=[CH:17][CH2:18][NH:19][C:20]([CH2:21][CH2:22][CH2:23][S:34][c:29]3[n:28][c:27]([NH2:26])[cH:32][c:31]([NH2:33])[n:30]3)=[O:25])[n:11][cH:12][cH:13]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
3
Sources & evidence
- ORD record
- ord-183d4a1a082f4d5eb7e22f8a1245b174
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…