2-Bromo-4-fluoroanisole → (2-Amino-6-chloro-pyridin-3-yl)-(5-fluoro-2-methoxy-phenyl)-methanone

HRID 1127518Notes

Reaction equation

HRID 1127518 reaction equation
[Br:15][c:16]1[c:17]([O:23][CH3:24])[cH:18][cH:19][c:20]([F:22])[cH:21]1.[NH2:1][c:2]1[c:3]([C:4](=[O:5])[N:6]([O:7][CH3:8])[CH3:9])[cH:10][cH:11][c:12]([Cl:14])[n:13]1>>[NH2:1][c:2]1[c:3]([C:4](=[O:5])[c:16]2[c:17]([O:23][CH3:24])[cH:18][cH:19][c:20]([F:22])[cH:21]2)[cH:10][cH:11][c:12]([Cl:14])[n:13]1

Participants

3

Reactant 2

HCID 1362922-Bromo-4-fluoroanisoleHCID 585908242-Amino-6-chloro-N-methoxy-N-methyl-nicotinamide

Product 1

HCID 58590829(2-Amino-6-chloro-pyridin-3-yl)-(5-fluoro-2-methoxy-phenyl)-methanone

Sources & evidence

ORD record
ord-082237cd461b4f0cbc870baa82e41219
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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