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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1127519Generated: October 30, 2026

1,2-Dichloroethane → tert-butyl N-[5-[5-[(5-cyanopyridine-2-carbonyl)amino]-2-fluorophenyl]-5-(difluoromethyl)-6,7-dihydro-2H-1,4-oxazepin-3-yl]carbamate

https://huagongshe.com/reaction/1127519

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantDimethylformamideHCID 6228—
ReactantDiisopropylethylamineHCID 81531—
Reactant5-Cyanopyridine-2-carboxylic acidHCID 12400734—
ReactantRacemic [5-(5-amino-2-fluoro-phenyl)-5-difluoromethyl-2,5,6,7-tetrahydro-[1,4]oxazepin-3-yl]-carbamic acid tert-butyl esterHCID 66665339—
Producttert-butyl N-[5-[5-[(5-cyanopyridine-2-carbonyl)amino]-2-fluorophenyl]-5-(difluoromethyl)-6,7-dihydro-2H-1,4-oxazepin-3-yl]carbamateHCID 66666437—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-2576793780d240c6a359641d42b6ef04
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)