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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1127532Generated: October 30, 2026

Cyanide → Tert-butyl 4-[2-(3-cyanophenyl)-2-(1-hydroxycyclohexyl)ethyl]piperazine-1-carboxylate

https://huagongshe.com/reaction/1127532

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyanideHCID 5975—
ReactantDimethylformamideHCID 6228—
ReactantPalladiumHCID 23938—
ReactantZincHCID 23994—
ReactantZinc(2+)HCID 32051—
ReactantDibenzylidene acetoneHCID 95417—
ReactantTert-butyl 4-[2-(3-bromophenyl)-2-(1-hydroxycyclohexyl)ethyl]piperazine-1-carboxylateHCID 68852390—
ProductTert-butyl 4-[2-(3-cyanophenyl)-2-(1-hydroxycyclohexyl)ethyl]piperazine-1-carboxylateHCID 68851916—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-ddfacad3aff44d418d70d252770ff149
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)