5-(2-Chloro-5-fluorophenyl)-1-(2,6-dichlorophenyl)-3,4-dihydro-7-methoxy-2(1H)-quinolinone → 5-(2-Chloro-5-fluorophenyl)-1-(2,6-dichlorophenyl)-3,4-dihydro-7-hydroxy-2(1H)-quinolinone

HRID 1127619Notes

Reaction equation

HRID 1127619 reaction equation
[Cl:1][c:2]1[c:3](-[c:9]2[c:10]3[c:15]([cH:16][c:17]([O:19][CH3:20])[cH:18]2)[N:14]([c:21]2[c:22]([Cl:28])[cH:23][cH:24][cH:25][c:26]2[Cl:27])[C:13](=[O:29])[CH2:12][CH2:11]3)[cH:4][c:5]([F:8])[cH:6][cH:7]1.[Cl:30][c:31]1[cH:32][cH:33][cH:34][c:35]([Cl:36])[c:37]1[N:38]1[c:39]2[c:40]([c:41](-[c:42]3[cH:43][cH:44][c:45]([F:46])[cH:47][c:48]3[F:49])[cH:50][c:51]([OH:52])[cH:53]2)[CH2:54][CH2:55][C:56]1=[O:57]>>[Cl:1][c:2]1[c:3](-[c:9]2[c:10]3[c:15]([cH:16][c:17]([OH:19])[cH:18]2)[N:14]([c:21]2[c:22]([Cl:28])[cH:23][cH:24][cH:25][c:26]2[Cl:27])[C:13](=[O:29])[CH2:12][CH2:11]3)[cH:4][c:5]([F:8])[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 226480755-(2-Chloro-5-fluorophenyl)-1-(2,6-dichlorophenyl)-3,4-dihydro-7-methoxy-2(1H)-quinolinoneHCID 226480931-(2,6-Dichlorophenyl)-5-(2,4-difluorophenyl)-3,4-dihydro-7-hydroxy-2(1H)-quinolinone

Product 1

HCID 226480905-(2-Chloro-5-fluorophenyl)-1-(2,6-dichlorophenyl)-3,4-dihydro-7-hydroxy-2(1H)-quinolinone

Sources & evidence

ORD record
ord-58d3249886a24d5bb921ddcf2ee2338d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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