Methanol → 6-chloro-4'-[5-chloro-2-(1-ethyl-1-methanesulfonylaminocarbonyl-propoxy)-phenyl]-2'-(5-chloro-2-methyl-phenyl)-spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione
Reaction equation
[C:1](=[O:2])([CH3:3])[N:4]1[C:5](=[O:48])[C:6]2([c:7]3[cH:8][cH:9][c:10]([Cl:13])[cH:11][c:12]31)[CH:14]([c:40]1[c:41]([CH3:47])[cH:42][cH:43][c:44]([Cl:46])[cH:45]1)[NH:15][C:16](=[O:39])[CH2:17][CH:18]2[c:19]1[c:20]([O:26][C:27]([CH2:28][CH3:29])([C:30](=[O:31])[NH:32][S:33](=[O:34])(=[O:35])[CH3:36])[CH2:37][CH3:38])[cH:21][cH:22][c:23]([Cl:25])[cH:24]1.[CH3:52][OH:53].[Na+:50].[OH-:49].[OH2:51]>>[NH:4]1[C:5](=[O:48])[C:6]2([c:7]3[cH:8][cH:9][c:10]([Cl:13])[cH:11][c:12]31)[CH:14]([c:40]1[c:41]([CH3:47])[cH:42][cH:43][c:44]([Cl:46])[cH:45]1)[NH:15][C:16](=[O:39])[CH2:17][CH:18]2[c:19]1[c:20]([O:26][C:27]([CH2:28][CH3:29])([C:30](=[O:31])[NH:32][S:33](=[O:34])(=[O:35])[CH3:36])[CH2:37][CH3:38])[cH:21][cH:22][c:23]([Cl:25])[cH:24]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-5372d19d11ba46a28e15a7cc2213dae0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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