Methanol → 5-Ethyl-6-trifluoromethyl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([CH:21]=[CH2:22])[c:13]([C:17]([F:18])([F:19])[F:20])[cH:14][c:15]2[CH2:16]1.[CH3:25][OH:26].[H:23][H:24]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([CH2:21][CH3:22])[c:13]([C:17]([F:18])([F:19])[F:20])[cH:14][c:15]2[CH2:16]1Participants
4
Sources & evidence
- ORD record
- ord-2099840e7baa438d8b49eb744e0fa7ba
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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