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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1127772Generated: October 25, 2026

Ethanol → 4-[4-(2,6-Difluoro-benzoylamino)-phenyl]-5-methyl-thiophene-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/1127772

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
ReactantTolueneHCID 1140—
ReactantEthyl AcetateHCID 8857—
ReactantPalladiumHCID 23938—
Reactant2,6-difluoro-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]benzamideHCID 53414211—
ReactantMethyl 4-iodo-5-methylthiophene-2-carboxylateHCID 59014058—
Product4-[4-(2,6-Difluoro-benzoylamino)-phenyl]-5-methyl-thiophene-2-carboxylic acid methyl esterHCID 24876709—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-5d42c3cde01b4dab8c680191603d8503
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)