Methyl 2-(2-chloroethoxy)benzoate → 2-(2-{4-[1-(5-chlorothiophen-2-ylmethyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]piperidin-1-yl}ethoxy)benzoic acid methyl ester

HRID 1127792Notes

Reaction equation

HRID 1127792 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:7][n:8]2[cH:9][c:10]([CH:17]3[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]3)[c:11]3[c:12]2[n:13][cH:14][cH:15][cH:16]3)[s:6]1.[Cl:23][CH2:24][CH2:25][O:26][c:27]1[c:28]([C:29](=[O:30])[O:31][CH3:32])[cH:33][cH:34][cH:35][cH:36]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:7][n:8]2[cH:9][c:10]([CH:17]3[CH2:18][CH2:19][N:20]([CH2:24][CH2:25][O:26][c:27]4[c:28]([C:29](=[O:30])[O:31][CH3:32])[cH:33][cH:34][cH:35][cH:36]4)[CH2:21][CH2:22]3)[c:11]3[c:12]2[n:13][cH:14][cH:15][cH:16]3)[s:6]1

Participants

3

Reactant 2

HCID 9837283Methyl 2-(2-chloroethoxy)benzoateHCID 179729751-(5-chlorothiophen-2-ylmethyl)3-piperidin-4-yl-1H-pyrrolo[2,3-b]pyridine

Product 1

HCID 688943472-(2-{4-[1-(5-chlorothiophen-2-ylmethyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]piperidin-1-yl}ethoxy)benzoic acid methyl ester

Sources & evidence

ORD record
ord-c872247b636b4cf19d1c4a0039120f2b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…