Acetonitrile → N-(4-(7-methoxy-1,5-naphthyridin-4-yloxy)phenyl)-4-(4-(2-(triethylsilyl)ethynyl)phenyl)phthalazin-1-amine
Reaction equation
[C:38](=[O:39])([O-:40])[O-:41].[C:62](#[N:63])[CH3:64].[C:65](#[N:66])[CH3:67].[CH2:50]([CH3:51])[Si:52]([CH2:53][CH3:54])([CH2:55][CH3:56])[C:57]#[CH:58].[CH3:59][C:60]#[N:61].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][n:10][c:11]([NH:18][c:19]3[cH:20][cH:21][c:22]([O:25][c:26]4[cH:27][cH:28][n:29][c:30]5[cH:31][c:32]([O:36][CH3:37])[cH:33][n:34][c:35]45)[cH:23][cH:24]3)[c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]23)[cH:6][cH:7]1.[Cl:68][Pd:69][Cl:70].[Cs+:42].[Cs+:43].[O:44]1[CH2:45][CH2:46][O:47][CH2:48][CH2:49]1>>[c:2]1([C:58]#[C:57][Si:52]([CH2:50][CH3:51])([CH2:53][CH3:54])[CH2:55][CH3:56])[cH:3][cH:4][c:5](-[c:8]2[n:9][n:10][c:11]([NH:18][c:19]3[cH:20][cH:21][c:22]([O:25][c:26]4[cH:27][cH:28][n:29][c:30]5[cH:31][c:32]([O:36][CH3:37])[cH:33][n:34][c:35]45)[cH:23][cH:24]3)[c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]23)[cH:6][cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-61a9be67bcb649e3b8f51b0a2c47fd11
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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