1-(4-(Trifluoromethyl)phenyl)piperazine → N-[4-(5-bromo-7-methyl-1,3-benzoxazol-2-yl)phenyl]-2-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]acetamide
Reaction equation
[Br:1][CH2:2][C:3](=[O:4])[NH:5][c:6]1[cH:7][cH:8][c:9](-[c:12]2[o:13][c:14]3[c:15]([n:16]2)[cH:17][c:18]([Br:22])[cH:19][c:20]3[CH3:21])[cH:10][cH:11]1.[F:23][C:24]([c:25]1[cH:26][cH:27][c:28]([N:31]2[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]2)[cH:29][cH:30]1)([F:37])[F:38]>>[CH2:2]([C:3](=[O:4])[NH:5][c:6]1[cH:7][cH:8][c:9](-[c:12]2[o:13][c:14]3[c:15]([n:16]2)[cH:17][c:18]([Br:22])[cH:19][c:20]3[CH3:21])[cH:10][cH:11]1)[N:34]1[CH2:33][CH2:32][N:31]([c:28]2[cH:27][cH:26][c:25]([C:24]([F:23])([F:37])[F:38])[cH:30][cH:29]2)[CH2:36][CH2:35]1Participants
3
Sources & evidence
- ORD record
- ord-c8bfaa9e514643ae9e95e739dbc28afb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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