7-Tert.-butyl-5-(4-chloro-phenyl)-3-iodo-pyrazolo[1,5-a]pyrimidine → 5-[7-tert.-Butyl-5-(4-chloro-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid amide

HRID 1128078Notes

Reaction equation

HRID 1128078 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7](-[c:15]2[cH:16][cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[n:8][c:9]2[n:10]1[n:11][cH:12][c:13]2[I:14].[C:22](#[CH:23])[c:24]1[cH:25][cH:26][c:27]([S:29](=[O:30])(=[O:31])[NH2:32])[s:28]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7](-[c:15]2[cH:16][cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[n:8][c:9]2[n:10]1[n:11][cH:12][c:13]2[C:23]#[C:22][c:24]1[cH:25][cH:26][c:27]([S:29](=[O:30])(=[O:31])[NH2:32])[s:28]1

Participants

3

Reactant 2

HCID 670002247-Tert.-butyl-5-(4-chloro-phenyl)-3-iodo-pyrazolo[1,5-a]pyrimidineHCID 860437955-Ethynylthiophene-2-sulfonamide

Product 1

HCID 670010355-[7-tert.-Butyl-5-(4-chloro-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid amide

Sources & evidence

ORD record
ord-64a3ae72946c42b388f6cce1631b6f03
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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