2,2,3,3-Tetrafluoro-1,4-benzodioxin-6-amine → N-(2,2,3,3-tetrafluorobenzodioxan-6-yl) 3-[(1H-Pyrrolo[2,3-b]pyridin-3-ylmethyl)amino]thiophene-2-carboxamide

HRID 1128385Notes

Reaction equation

HRID 1128385 reaction equation
[NH2:1][c:2]1[c:3]([C:7](=[O:8])[NH:9][c:10]2[cH:11][c:12]3[c:13]([cH:22][cH:23]2)[O:14][C:15]([F:20])([F:21])[C:16]([F:18])([F:19])[O:17]3)[s:4][cH:5][cH:6]1.[NH2:24][c:25]1[cH:26][cH:27][c:28]2[c:37]([cH:38]1)[O:36][C:33]([F:34])([F:35])[C:30]([F:31])([F:32])[O:29]2.[nH:39]1[cH:40][c:41]([CH:48]=[O:49])[c:42]2[cH:43][cH:44][cH:45][n:46][c:47]12>>[NH:1]([c:2]1[c:3]([C:7](=[O:8])[NH:9][c:10]2[cH:11][c:12]3[c:13]([cH:22][cH:23]2)[O:14][C:15]([F:20])([F:21])[C:16]([F:18])([F:19])[O:17]3)[s:4][cH:5][cH:6]1)[CH2:48][c:41]1[cH:40][nH:39][c:47]2[c:42]1[cH:43][cH:44][cH:45][n:46]2

Participants

4

Reactant 3

HCID 27765742,2,3,3-Tetrafluoro-1,4-benzodioxin-6-amineHCID 53728121H-Pyrrolo[2,3-b]pyridine-3-carbaldehydeHCID 86594333N-(2,2,3,3-tetrafluorobenzodioxan-6-yl) 3-aminothiophene-2-carboxamide

Product 1

HCID 10480185N-(2,2,3,3-tetrafluorobenzodioxan-6-yl) 3-[(1H-Pyrrolo[2,3-b]pyridin-3-ylmethyl)amino]thiophene-2-carboxamide

Sources & evidence

ORD record
ord-dd2dc94b6af946319117703b4b45d37f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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