3-Hydroxyazetidine → 4-(3-Hydroxy-azetidine-1-carbonyl)-1-(3-methoxy-benzyl)-1H-benzoimidazole-2-carboxylic acid (1-isopropyl-piperidin-4-yl)-amide

HRID 1128395Notes

Reaction equation

HRID 1128395 reaction equation
[CH:1]([CH3:2])([CH3:3])[N:4]1[CH2:5][CH2:6][CH:7]([NH:10][C:11](=[O:12])[c:13]2[n:14][c:15]3[c:16]([n:17]2[CH2:18][c:19]2[cH:20][c:21]([O:25][CH3:26])[cH:22][cH:23][cH:24]2)[cH:27][cH:28][cH:29][c:30]3[C:31](=[O:32])[OH:33])[CH2:8][CH2:9]1.[OH:34][CH:35]1[CH2:36][NH:37][CH2:38]1>>[CH:1]([CH3:2])([CH3:3])[N:4]1[CH2:5][CH2:6][CH:7]([NH:10][C:11](=[O:12])[c:13]2[n:14][c:15]3[c:16]([n:17]2[CH2:18][c:19]2[cH:20][c:21]([O:25][CH3:26])[cH:22][cH:23][cH:24]2)[cH:27][cH:28][cH:29][c:30]3[C:31](=[O:32])[N:37]2[CH2:36][CH:35]([OH:34])[CH2:38]2)[CH2:8][CH2:9]1

Participants

3

Reactant 2

HCID 15142903-HydroxyazetidineHCID 670118282-(1-Isopropyl-piperidin-4-ylcarbamoyl)-1-(3-methoxy-benzyl)-1H-benzoimidazole-4-carboxylic acid

Product 1

HCID 670123934-(3-Hydroxy-azetidine-1-carbonyl)-1-(3-methoxy-benzyl)-1H-benzoimidazole-2-carboxylic acid (1-isopropyl-piperidin-4-yl)-amide

Sources & evidence

ORD record
ord-d63cc979aedf43cc9c1b9ac89d58cf9e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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