Toluene → (5-Pyrazin-2-yl-benzofuran-2-yl)-methanol

HRID 1128461Notes

Reaction equation

HRID 1128461 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:7][c:8]([CH2:10][OH:11])[o:9]2)[cH:12]1.[CH2:13]([Sn:14]([CH2:15][CH2:16][CH2:17][CH3:24])([c:18]1[n:19][cH:20][cH:21][n:22][cH:23]1)[CH2:25][CH2:26][CH2:27][CH3:28])[CH2:29][CH2:30][CH3:31].[CH3:32][c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1.[cH:39]1[cH:40][cH:41][c:42]([P:43]([Pd:44]([P:45]([c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)([c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)([P:64]([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)([c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)[c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)[P:83]([c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)([c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)[c:96]2[cH:97][cH:98][cH:99][cH:100][cH:101]2)([c:102]2[cH:103][cH:104][cH:105][cH:106][cH:107]2)[c:108]2[cH:109][cH:110][cH:111][cH:112][cH:113]2)[cH:114][cH:115]1>>[c:2]1(-[c:18]2[n:19][cH:20][cH:21][n:22][cH:23]2)[cH:3][cH:4][c:5]2[c:6]([cH:7][c:8]([CH2:10][OH:11])[o:9]2)[cH:12]1

Participants

5

Reactant 4

HCID 1140TolueneHCID 27373162-(Tributylstannyl)pyrazineHCID 2795537(5-Bromo-1-benzofuran-2-yl)methanolHCID 178420554HCID 178420554, compound

Product 1

HCID 22396303(5-Pyrazin-2-yl-benzofuran-2-yl)-methanol

Sources & evidence

ORD record
ord-bf2a6c2d19c14a16943c26550fa91c14
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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