N-(5-fluoro-2-oxo-2,3-dihydro-1H-indol-6-yl)-2-hydroxy-2-methyl-propionamide → N-{5-fluoro-3-[3-methyl-5-(2-morpholin-4-yl-ethyl)-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indol-6-yl}-2-hydroxy-2-methyl-propionamide
Reaction equation
[CH3:1][c:2]1[c:3]([CH:20]=[O:21])[nH:4][c:5]2[c:6]1[C:7](=[O:19])[N:8]([CH2:11][CH2:12][N:13]1[CH2:14][CH2:15][O:16][CH2:17][CH2:18]1)[CH2:9][CH2:10]2.[F:22][c:23]1[cH:24][c:25]2[c:29]([cH:30][c:31]1[NH:32][C:33]([C:34]([CH3:35])([CH3:36])[OH:37])=[O:38])[NH:28][C:27](=[O:39])[CH2:26]2>>[CH3:1][c:2]1[c:3]([CH:20]=[C:26]2[c:25]3[cH:24][c:23]([F:22])[c:31]([NH:32][C:33]([C:34]([CH3:35])([CH3:36])[OH:37])=[O:38])[cH:30][c:29]3[NH:28][C:27]2=[O:39])[nH:4][c:5]2[c:6]1[C:7](=[O:19])[N:8]([CH2:11][CH2:12][N:13]1[CH2:14][CH2:15][O:16][CH2:17][CH2:18]1)[CH2:9][CH2:10]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-be1fb0fbab9443869ae0f1ee4597fc20
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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