Potassium Cation → N-[1-cyclohexyl-3-[4-(2-methoxyphenyl)piperidin-1-yl]propan-2-yl]-N,2,2-trimethylpropanamide

HRID 1128819Notes

Reaction equation

HRID 1128819 reaction equation
[C:1](=[O:2])([O-:3])[O-:4].[CH3:32][C:33]([C:34](=[O:35])[Cl:36])([CH3:37])[CH3:38].[CH:7]1([CH2:13][CH:14]([CH2:15][N:16]2[CH2:17][CH2:18][CH:19]([c:22]3[c:23]([O:28][CH3:29])[cH:24][cH:25][cH:26][cH:27]3)[CH2:20][CH2:21]2)[NH:30][CH3:31])[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12]1.[Cl:39][CH2:40][Cl:41].[K+:5].[K+:6].[OH2:42]>>[CH:7]1([CH2:13][CH:14]([CH2:15][N:16]2[CH2:17][CH2:18][CH:19]([c:22]3[c:23]([O:28][CH3:29])[cH:24][cH:25][cH:26][cH:27]3)[CH2:20][CH2:21]2)[N:30]([CH3:31])[C:34]([C:33]([CH3:32])([CH3:37])[CH3:38])=[O:35])[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6344DichloromethaneHCID 19660Carbonate IonHCID 62493Pivaloyl chlorideHCID 178483174HCID 178483174, compound

Product 1

HCID 178489303N-[1-cyclohexyl-3-[4-(2-methoxyphenyl)piperidin-1-yl]propan-2-yl]-N,2,2-trimethylpropanamide

Sources & evidence

ORD record
ord-46c2a7a45b5e46fea5e56c9fa85a05a8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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