3-(4-Piperidinyl)-1H-indole → 3-(difluoromethyl)-6-[4-(1H-indol-3-yl)piperidin-1-yl][1,2,4]triazolo[4,3-b]pyridazine
Reaction equation
[F:16][CH:17]([c:18]1[n:19][n:20][c:21]2[n:22]1[n:23][c:24]([N:27]1[CH2:28][CH2:29][NH:30][CH2:31][CH2:32]1)[cH:25][cH:26]2)[F:33].[NH:1]1[CH2:2][CH2:3][CH:4]([c:7]2[cH:8][nH:9][c:10]3[cH:11][cH:12][cH:13][cH:14][c:15]23)[CH2:5][CH2:6]1>>[N:1]1([c:24]2[n:23][n:22]3[c:18]([CH:17]([F:16])[F:33])[n:19][n:20][c:21]3[cH:26][cH:25]2)[CH2:2][CH2:3][CH:4]([c:7]2[cH:8][nH:9][c:10]3[cH:11][cH:12][cH:13][cH:14][c:15]23)[CH2:5][CH2:6]1Participants
3
Sources & evidence
- ORD record
- ord-5384d1a6a1844ea38ef58ef910278d96
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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