Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Fluoroquinolonic acid → 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(3'-acetamido-5'-methylpvrrolidin-1-yl)-4-oxo-quinoline-3-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Fluoroquinolonic acid | HCID 483180 | — |
| 반응물 | 3-Acetamido-5-methylpyrrolidine | HCID 19957206 | — |
| 생성물 | 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(3'-acetamido-5'-methylpvrrolidin-1-yl)-4-oxo-quinoline-3-carboxylic acid | HCID 10134799 | — |
반응 단계
The condensation of 1-cyclopropyl-6-fluoro-7-chloro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid with 3-acetamido-5-methylpyrrolidine in a similar manner as described in example 1 give the titled product. Yield (68%), m.p 270–72° C., C20H22FN3O4, m/z 388 (M+1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07098219B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-52e4e58da95a46789156c6f37fe17043 |
| 출처 메모 | uspto-grants-2006_08 |