Pyridine → diethyl 4-(4-chloro-2-nitrobenzoyl)-1H-pyrazole-3,5-dicarboxylate

HRID 112916Notes

Reaction equation

HRID 112916 reaction equation
[CH2:38]([Cl:39])[Cl:40].[Cl:11][c:12]1[cH:13][c:14]([N+:35](=[O:36])[O-:37])[c:15]([CH:18]([c:19]2[c:20]([C:29](=[O:30])[O:31][CH2:32][CH3:33])[n:21][nH:22][c:23]2[C:24](=[O:25])[O:26][CH2:27][CH3:28])[OH:34])[cH:16][cH:17]1.[O:7]=[Cr:8](=[O:9])=[O:10].[cH:1]1[cH:2][cH:3][n:4][cH:5][cH:6]1>>[Cl:11][c:12]1[cH:13][c:14]([N+:35](=[O:36])[O-:37])[c:15]([C:18]([c:19]2[c:20]([C:29](=[O:30])[O:31][CH2:32][CH3:33])[nH:21][n:22][c:23]2[C:24](=[O:25])[O:26][CH2:27][CH3:28])=[O:34])[cH:16][cH:17]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 14915Chromium TrioxideHCID 18358881Diethyl 4-[(4-chloro-2-nitrophenyl)hydroxymethyl]-1H-pyrazole-3,5-dicarboxylate

Product 1

HCID 18358912diethyl 4-(4-chloro-2-nitrobenzoyl)-1H-pyrazole-3,5-dicarboxylate

Sources & evidence

ORD record
ord-727e5de24fdb4fe7b7ba3902247dcaf9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…