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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1129265Generated: October 31, 2026

Trifluoroacetic acid → 6-chloro-4'-(3-chlorophenyl)-2'-(5-fluoro-2-methylphenyl)-1'-(3-pyrrolidin-1-yl-propyl)spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione

https://huagongshe.com/reaction/1129265

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantPyrrolidineHCID 31268—
Reactant(1-Methoxyethyl)(trimethyl)silaneHCID 22400412—
Reactant6-chloro-4'-(3-chlorophenyl)-1'-(3-chloropropyl)-6'-(5-fluoro-2-methylphenyl)spiro[1H-indole-3,5'-piperidine]-2,2'-dioneHCID 77580789—
Product6-chloro-4'-(3-chlorophenyl)-2'-(5-fluoro-2-methylphenyl)-1'-(3-pyrrolidin-1-yl-propyl)spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dioneHCID 74370455—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-ad690beab862432581fc0b0cce2f382d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)