Acetate → Ethyl 2-(butan-2-ylamino)-6-methoxypyridine-4-carboxylate

HRID 1129739Notes

Reaction equation

HRID 1129739 reaction equation
[C:66](=[O:67])([O-:68])[O-:69].[C:79]([O-:80])(=[O:81])[CH3:82].[C:84]([O-:85])(=[O:86])[CH3:87].[CH2:6]([CH3:7])[O:8][C:9]([c:10]1[cH:11][c:12]([Cl:18])[n:13][c:14]([O:16][CH3:17])[cH:15]1)=[O:19].[CH3:72][c:73]1[cH:74][cH:75][cH:76][cH:77][cH:78]1.[CH:1]([CH3:2])([CH2:3][CH3:4])[NH2:5].[Cs+:70].[Cs+:71].[Pd+2:83].[c:20]1([P:21]([c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[c:28]2[cH:29][cH:30][c:31]3[c:32]([cH:33][cH:34][cH:35][cH:36]3)[c:37]2-[c:38]2[c:39]3[c:40]([cH:41][cH:42][cH:43][cH:44]3)[cH:45][cH:46][c:47]2[P:48]([c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)[cH:61][cH:62][cH:63][cH:64][cH:65]1>>[CH:1]([CH3:2])([CH2:3][CH3:4])[NH:5][c:12]1[cH:11][c:10]([C:9]([O:8][CH2:6][CH3:7])=[O:19])[cH:15][c:14]([O:16][CH3:17])[n:13]1

Participants

9

Reactant 8

HCID 175Acetate2×HCID 1140TolueneHCID 19660Carbonate IonHCID 24874Sec-ButylamineHCID 104967Cesium cation2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 634876Binap, (A+-)-HCID 13611989Ethyl 2-chloro-6-methoxyisonicotinate

Product 1

HCID 68815379Ethyl 2-(butan-2-ylamino)-6-methoxypyridine-4-carboxylate

Sources & evidence

ORD record
ord-7bc1c0ce74bc4f3eb4b86a41243f6cb9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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